et al., “Green Oxidation of Indoles Using Halide Catalysis”, Nature Communications, 10:4754,, Oct. Halford, B., “Pfizer's novel COVID-19 antiviral heads to clinical trials-The small molecule targets coronavirus 3CL protease and is active against multiple coronaviruses in cell studies”, Chem. News, online at, (a version appeared in 99(13)), Apr. Halford, B., “Pfizer unveils its oral SARS-00V-2 inhibitor-The antiviral candidate is the first orally administered compound to enter clinical trials that targets the virus's main protease”, Chem. et al., “Discovery and Optimization of a Novel Spiropyrrolidine Inhibitor of B-Secretase (BACE1) through Fragment-Based Drug Design”, J. PROTEASE INHIBITORS FOR TREATMENT OR PREVENTION OF CORONAVIRUS DISEASEĪNTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONSĮfremov, I. SMALL MOLECULE INHIBITORS OF SARS-COV-2 VIRAL REPLICATION AND USES THEREOF INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION MACROCYCLIC AND PEPTIDOMIMETIC COMPOUNDS AS BROAD-SPECTRUM ANTIVIRALS AGAINST 3C OR 3C-LIKE PROTEASES OF PICORNAVIRUSES, CALICIVIRUSES AND CORONAVIRUSESĬOMPOUNDS THAT INHIBIT 3C AND 3CL PROTEASES AND METHODS OF USE THEREOF PROTEASE INHIBITORS FOR CORONAVIRUSES AND SARS-COV AND THE USE THEREOFĪNTICORONVIRAL COMPOUNDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES AND MATERIALS FOR THEIR SYNTHESISĪNTICORONAVIRAL COMPOUNDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES AND MATERIALS FOR THEIR SYNTHESISĬURCUMIN COMPOUNDS AND THEIR PREPARATIONS THEREOF Protease screening methods and proteases identified therebyīROAD-SPECTRUM ANTIVIRALS AGAINST 3C OR 3C-LIKE PROTEASES OF PICORNAVIRUS-LIKE SUPERCLUSTER: PICORNAVIRUSES, CALICIVIRUSES AND CORONAVIRUSESĬrystal structure of human coronavirus 229E main proteinase and uses for developing SARS inhibitors Macrocyclic and peptidomimetic compounds as broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, caliciviruses and coronaviruses Recombinant baculovirus vector and uses thereof Recombinant expression of multiprotein complexes using polygenesīroad-spectrum antivirals against 3C or 3C-like proteases of picornavirus-like supercluster: picornaviruses, caliciviruses and coronaviruses Isatin derivatives, pharmaceutical compositions thereof, and methods of use thereof Reprogramming T cells and hematopoietic cellsīroad-spectrum non-covalent coronavirus protease inhibitors Generation of induced pluripotent stem cells from small volumes of peripheral blood Multipartite signaling proteins and uses thereof Method for transmitting information for LTE-WLAN aggregation system and a device thereforĬyclic keto-amide compounds as calpain modulators and methods of production and use thereof Method for analysing the interaction of nucleotide sequences in a three-dimensional DNA structureĬalpain modulators and therapeutic uses thereofĬBLB endonuclease variants, compositions, and methods of use Minimal volume reprogramming of mononuclear cells Methods of treating SARS Cov-2 virus with protocatechuic acid Small molecule therapeutic inhibitors against picornaviruses, caliciviruses, and coronaviruses Peptidomimetics for the treatment of norovirus infection Protease transition state inhibitor prodrugs Methods of treating coronavirus infection Porcine epidemic diarrhea virus strains and immunogenic compositions therefrom Sirna/nanoparticle formulations for treatment of middle-east respiratory syndrome coronaviral infection Inhibitors of cysteine proteases and methods of use thereof INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Peptidomimetics for the treatment of coronavirus and picornavirus infections
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